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Certified Addictions Registered Nurse (CARN) Advanced Practice (AP) Practice Test 2026 - Free CARN AP Practice Questions and Study Guide course image
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  • Methadone is an opioid: antagonist or agonist?
  • True or False: Heavy and binge drinking rates have shown a significant increase in recent trends.
  • What percentage of adults have had exposure to alcohol?
  • How quickly can tolerance develop to benzodiazepines with continued use?
  • Which of the following is a documented effect of topiramate in alcohol use disorder treatment?
  • Bupropion is commonly marketed under which brand name?
  • Stage of change in which people are unwilling to change their behavior?
  • Which of the following are common symptoms of alcohol withdrawal?
  • Which statement identifies a NOT typical symptom of methamphetamine withdrawal?
  • Is the YFAS self-reported?
  • Approximately how long does it typically take to complete the YFAS?
  • Methamphetamine is a blank form of dopamine.
  • Which of the following is a tobacco withdrawal symptom?
  • Varenicline reduces the effects of nicotine by blocking receptors.
  • Which statement about the YFAS is accurate?
  • Which medication blocks opioid receptors to reduce the rewarding effects of alcohol?
  • What does the biopsychosocial model describe?
  • What is an antagonist?
  • ALDH5A1 is best described as which type of biomolecule?
  • Phencyclidine is the full name of which drug?
  • What is the recommended maximum number of drinks per day for adults?
  • Which of the following statements is true regarding opiates and opioids?
  • Which statement best describes a typical YFAS administration time? (Most true statement)
  • Amphetamine toxicity causes BLANK pupils.
  • In this stage, people have recently changed their behavior (defined as within the last 6 months) and intend to keep moving forward with that behavior change.
  • Which stage defined as having recently changed behavior and intending to maintain that change is the:
  • How long does it take to complete the Yale Food Addiction Scale (YFAS)?
  • In Motivational Interviewing, which element is central to evoking change?
  • What is the typical daily dose range for bupropion when used for tobacco cessation?
  • Benzodiazepines bind at what receptor?
  • Delirium tremens usually begins how many days after surgery?
  • Which medication is associated with the brand Wellbutrin?
  • What is the name brand of Bupropion?
  • According to the DSM-5 criteria, how many criteria indicate a mild substance use disorder?
  • What is the typical duration of LSD effects?
  • Binge drinking - amount for men and women.
  • The Hooked on Nicotine Checklist (HONC) is a tool used to assess risk of what?
  • What is the treatment for mild to moderate amphetamine overdose?
  • Which counseling point is essential for disulfiram use?
  • In relation to alcohol withdrawal, which mechanism is listed for quetiapine in the material?
  • Amphetamines increase the activity of which neurotransmitters?
  • Stage of change in which people are considering changing behavior in the next 6 months?
  • Which of the following is NOT listed as a tobacco withdrawal symptom?
  • How many days before cessation should patients start bupropion?
  • Chronic cocaine use can result in which of the following nasal findings?
  • Which medication blocks opioid receptors to reduce the pleasant effects of alcohol?
  • How many criteria must be met to qualify as severe SUD?
  • How many DSM-5 criteria indicate a mild substance use disorder?
  • Quetiapine (Seroquel) is associated with affecting which neurotransmitter systems?
  • gamma-Glutamyl transferase (GGT) serves as a biomarker for which clinical parameter?
  • For an amphetamine overdose, what is the recommended treatment if the patient presents within one hour?
  • The Inventory of Drinking Situations is used to identify emotional, cognitive, and social factors that may precipitate drinking.
  • What is the brand name for bupropion?
  • What causes hangover-like symptoms when drinking while taking disulfiram?
  • What is the 12-month prevalence rate of nicotine use?
  • Which medication is considered the most effective for treating nicotine dependence?
  • Nicotine's effects in the central nervous system include which of the following?
  • Acamprosate is indicated for which purpose?
  • What is the primary goal of cognitive-behavioral therapy (CBT)?
  • Which of the following is the generic name for the opioid overdose reversal agent?
  • Acamprosate (Campral) helps abstinence from alcohol by what mechanism?
  • Which medication is described as helping abstinence from alcohol by dampening glutamate activity?
  • Acamprosate (Campral) dosing is which of the following?
  • Delirium tremens typically begins within how many hours after the last drink?
  • Which statement correctly differentiates opioids from opiates?
  • Gamma glutamyl transferase (GGT) is best described as which of the following?
  • PCP acts primarily as an antagonist at which receptor?
  • Which brain structure is responsible for the reinforcing nature of opioid use?
  • In the CAGE questionnaire, what does the letter 'G' stand for?
  • Varenicline is best described as which of the following?
  • Which drug is associated with euphoria or rage, reddish skin, dilated pupils, nystagmus, and excitation?
  • Can patients smoke while using nicotine replacement therapy (NRT)?
  • Chronic cocaine use is associated with vasculitis-like syndromes similar to Raynaud's phenomenon. This statement is:
  • What is a partial agonist?
  • The amygdala plays an important role in which function?
  • Which of the following is a component of the OARS framework used in motivational interviewing?
  • Which type of data does the YFAS primarily rely on?
  • Which DSM-5 criterion refers to craving or spending a lot of time using?
  • The hallmark clinical feature of drug-induced thrombotic microangiopathy (DITMA) is which of the following?
  • Which of the following is a sign of benzodiazepine intoxication?
  • What is the lifetime risk of alcohol dependence?
  • Bupropion (Wellbutrin) increases which neurotransmitters?
  • Disulfiram blocks which enzyme in the brain?
  • What is the generic name of Narcan?
  • PCP is best described as which type of drug?
  • Daily naltrexone dosing for AUD is which?
  • What is the brand name for varenicline?
  • Which neurotransmitter is associated with speeding neural activity?
  • Which statement best describes a full agonist's effect at a receptor?
  • What is the brand name for acamprosate?
  • What does GABBA do?
  • Which statement is true about disulfiram and alcohol interactions?
  • Which assessment measures a patient's motivation to change drinking behavior?
  • In a case of opioid use disorder treated with buprenorphine, the most appropriate next step when there is concurrent benzodiazepine use and alcohol intake is to:
  • Which medication is a non-nicotine pharmacotherapy for nicotine dependence that increases dopamine and norepinephrine?
  • LSD is a hallucinogen that elevates activity of which neurotransmitter system?
  • What is Cocaine's mechanism of action?
  • To be eligible for naltrexone after opioid use, how long must a person be abstinent from all opioids, including buprenorphine?
  • Personalization in counseling refers to which concept?
  • Which term describes a molecule that increases a neurotransmitter's action?
  • Which of the following is a sign of opioid withdrawal?
  • What is the full name of PCP?
  • YFAS is named after which institution?
  • Which statement correctly describes the relationship between glutamate and GABA as described?
  • To start Naltrexone for AUD or OUD, abstinence from alcohol must be maintained for how long?
  • Which term describes a drug that produces a weaker response than a full agonist?
  • For an amphetamine overdose within one hour, which agent is advised?
  • In the CAGE questionnaire, what does the letter 'C' stand for?
  • Which statement best captures the core spirit of Motivational Interviewing?
  • Which of the following best describes the YFAS content?
  • Alprazolam (Xanax) is classified as which type of medication?
  • Which option correctly identifies the Yale Food Addiction Scale (YFAS)?
  • Which drug class is used to treat agitation, muscle rigidity, seizures, and hypertension associated with MDMA overdose?
  • What is the action of benzodiazepines in alcohol withdrawal management?
  • Bupropion is commonly used to treat which condition?
  • Which neurotransmitter is described as increasing pleasure or reinforcement?
  • The Coping Response Inventory assesses what?
  • Which medication is a full opioid agonist used in maintenance therapy?
  • What is the lifetime prevalence of nicotine use?
  • What is the maximum first dose allowed by law in a methadone maintenance program?
  • According to the material, a severe substance use disorder is indicated by more than how many criteria?
  • Which neurotransmitter is released in reward pathways and linked to reinforcement in the brain?
  • Which stage is defined by considering change within the next six months?
  • Which reflection response is best when a patient expresses concern about others judging them for smoking?
  • Acamprosate is used to maintain abstinence and reduce post-acute withdrawal symptoms. Which choice best reflects this statement?
  • Pharmacological treatment increases quit rates by approximately how many times?
  • Disulfiram (Antabuse) acts by...
  • Naltrexone is used to treat AUD by which mechanism?
  • What does glutamate do?
  • To be classified as having a substance use disorder per DSM-5, at least how many criteria must be met?
  • The Inventory of Drinking Situations is a 100-item self-report instrument.
  • Acamprosate should not be given in which impairment?
  • What buprenorphine dose was the patient advanced to in the described case?
  • Barbiturates are best described as what?
  • Heavy (At risk) Drinking - amount for men and women.
  • What gene is involved in alcohol flushing?
  • Which statement best describes the YFAS purpose?
  • In TTFC assessment, moderate tobacco use is defined as smoking within which minutes after waking?
  • In the Precontemplation stage of behavior change, how is the individual typically described?
  • Fentanyl is classified as which type of opioid?
  • DITMA is defined as which of the following?
  • Flumazenil is used to reverse which category of substances?
  • The peak effects of LSD typically occur within how many hours after onset?
  • In TTFC assessment, severe tobacco use is defined as tobacco use within how many minutes after waking?
  • Which statement accurately reflects the effect of pharmacological treatment on smoking cessation according to the material?
  • Disulfiram should be avoided with which everyday product due to potential alcohol content?
  • What is the first-line treatment for symptoms of acute stimulant-induced psychosis?
  • Baclofen (Lioresal) is best classified as what type of medication?
  • Which is a common cardiovascular symptom of opioid withdrawal?
  • What is the action of varenicline in smoking cessation?
  • What is the first-line treatment for delirium tremens?
  • Varenicline is marketed under which brand name?
  • The Situational Confidence Questionnaire consists of how many self-reported questions?
  • Which statement best describes the Hooked on Nicotine Checklist (HONC) in clinical use?
  • The half-life of nicotine is approximately how many hours?
  • Cannabis withdrawal symptoms listed include which of the following?
  • Which item is NOT part of the OARS framework?
  • In research on Motivational Interviewing with diverse communities, which statement best reflects effectiveness?
  • Which of the following is a DSM-5 criterion for a substance use disorder?
  • In Nicorette or generic gum, what factor determines the milligram dosing?
  • Methamphetamine is a blank form of dopamine.
  • Which statement about nicotine prevalence is true?
  • Which term describes a molecule that blocks receptor activation?
  • Which product should be avoided while taking disulfiram due to potential reaction with alcohol?
  • Disulfiram is a daily oral medication to sustain abstinence from alcohol; this is considered what type of therapy?
  • According to the 2018 National Survey on Drug Use and Health, the rate of heavy drinking is approximately:
  • What is the first-line treatment for acute psychosis?
  • The Situational Confidence Questionnaire (SCQ) measures adherence to treatment in patients with addiction.
  • Which medication is used as an opioid receptor antagonist for relapse prevention in opioid dependence?
  • Which of the following represents the standard size of one drink?
  • Who typically completes the Yale Food Addiction Scale?
  • Which of the following is a symptom of systemic anabolic steroid use in women?
  • Which medication is used to treat serotonin syndrome?
  • What is the primary objective of the Maintenance stage in the stage-of-change model described?
  • Which symptoms may occur when alcohol is consumed after taking disulfiram (Antabuse)?
  • What is the Yale Food Addiction Scale (YFAS) primarily designed to identify?
  • What is the most widely used stimulant?
  • The 5th stage of change focuses on preventing relapse and consolidating gains. Which stage is described?
  • What is the neuropharmacological pathway through which topiramate exerts its effects in alcohol use disorder?
  • Which stimulus causes the greatest peak dopamine release in the brain among the following options?
  • Amphetamines exert their effect by blocking the reuptake of which two neurotransmitters?
  • Which statement best describes what the YFAS aims to identify?
  • Which DSM-5 criterion refers to neglecting major life roles and social/interpersonal problems due to substance use?
  • Naltrexone is a mu opioid receptor BLANK.
  • What is the primary purpose of the CAGE questionnaire?
  • Endogenous opioids have what effect on pain and mood?
  • In the management of delirium tremens, which class of medications is commonly used?
  • Amnesia, severe dysarthria, and sometimes hypothermia are seen at which level?
  • Disulfiram works as a pharmacologic intervention primarily by causing a severe reaction when alcohol is consumed; this describes which concept?
  • Which instrument is described as assessing coping skills for relapse prevention?
  • In motivational interviewing, which technique involves reflecting the client's meaning and emotions back to them?
  • Buprenorphine is used in office-based treatment for which condition?
  • What is the approximate prevalence of inhalant use in adolescents?
  • Is concomitant use of varenicline with nicotine replacement therapy recommended?
  • LSD effects have the following onset, peak, and duration: onset 30–60 minutes; peak 2–4 hours; duration 8–12 hours. Which option matches this description?
  • Compared with nicotine replacement therapy or bupropion, varenicline has what quit rates?
  • Which of the following is a symptom of opioid withdrawal related to pupil size?
  • What is the pharmacologic action of disulfiram when alcohol is consumed?
  • What is the brand name associated with baclofen?
  • What type of assessment is the YFAS?
  • What gene is commonly involved in non-responsive patients on MOUD?
  • Benzo's activate the BLANK receptor causing sedation.
  • Which substance is used to treat serotonin syndrome?
  • Which of the following are among the most common symptoms of methamphetamine withdrawal?
  • PCP acts on which receptor type?
  • Above which blood alcohol level can be fatal?
  • Drowsiness is prevalent at what blood alcohol level?
  • What is the typical daily dose range for disulfiram?
  • When used for alcohol use disorders, topiramate is documented to do which of the following?
  • In the Contemplation stage, individuals are:
  • Which option identifies the substance that is NOT a stimulant category?
  • In the CAGE questionnaire, what does the letter 'A' stand for?
  • Which of the following is a contraindication to bupropion?
  • Delirium tremens is typically treated with which medication?
  • For starting Naltrexone in AUD/OUD, abstinence from alcohol must be maintained for how long prior to initiation?
  • Which neurotransmitter system is most directly linked to inhibitory control in the CNS, commonly targeted by sedatives including benzodiazepines?
  • The YFAS focuses on markers of substance dependence in relation to the consumption of what type of foods?
  • How long after the last drink can disulfiram be started?
  • How many items are on the SOCRATES self-report test?
  • Coma can occur at what blood alcohol level?
  • Which TTFC timeframe is associated with severe tobacco use?
  • At what blood alcohol level do signs of intoxication start to become obvious?
  • Which component of OARS involves restating what the client has said to ensure understanding?
  • Acamprosate (Campral) does what to GABA and glutamate levels?
  • In stimulant-induced psychosis, which class of medication is considered first-line treatment?
  • Bupropion (Wellbutrin) mimics the effects of nicotine by increasing which neurotransmitters?
  • What is the generic name for the medication marketed as Vivitrol?
  • Which statement about the Inventory of Drinking Situations is true?
  • GABRA6 is best described as which type of molecule?
  • Which medication is a partial opioid agonist used in maintenance therapy?
  • Analeptics are best described as drugs that do what?
  • What does increased endogenous opioids do?
  • GABA is excitatory or inhibitory?
  • Which statement best reflects proficiency in Motivational Interviewing practice?
  • Which trio represents the three stimulant drug categories?
  • Nervousness, tremor, agitation, and hypotension may occur from abrupt discontinuation of BLANK.
  • What does dopamine do?
  • Which medication is used for alcohol aversion therapy and is known by brand Antabuse?
  • Glutamate is excitatory or inhibitory?
  • Which statement by Steve is the best indicator of his readiness to change?
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